Listed are the pathologies that closely resemble each other, and these pathologies are the favourite questions in final FRCR part A exam.
AIDS-related cerebral lesion
Cerebral toxoplasmosis
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CNS Lymphoma
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1
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Most common lesion in AIDS
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2nd most common lesion in AIDS
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2
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Multiple<2cm font="" hypodense="" lesions="">
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Hyperdense/Isodense lesion
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3
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Predilection for basal ganglia
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Periventricular & Basal ganglia
Cross corpus callosum
Frequently abut/extend along ependymal surface (subependymal spread)
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4a
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Hemorrhage: Toxo > CNS Lymphoma
Solid / Ring-enhancing
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Immunocompromised:
Necrosis +/- Hemorrhage
Ring-enhancing (because of necrosis)
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4b
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Immunocompetent:
Moderate, uniform enhancement
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5
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Thallium scan: NO uptake
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Thallium scan: Avid uptake on SPECT
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6
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Higher T2/FLAIR SI
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↓ T2/FLAIR/T1
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7
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MR perfusion: Hypovascular
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MR perfusion: ↑ perfusion
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8
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MR: Difficult to distinguish in terms of signal features / pattern
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